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Updated: Jun 16, 2026

A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft
12:18

A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft

Published on: August 8, 2020

Allograft skin as a permanent tissue repair: to mesh or not?

Karsten Knobloch1, Peter M Vogt

  • 1Plastic, Hand, and Reconstructive Surgery; Hannover Medical School; Hannover, Germany.

Plastic and Reconstructive Surgery
|February 4, 2010
PubMed
Abstract

No abstract available in PubMed .

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...