Related Experiment Video
Updated: Jun 16, 2026
08:13
In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Clinical and technical considerations for stress myocardial perfusion imaging with multidetector computed tomography
Thanjavur K M Bragadeesh1, Michael D Shapiro
1Division of Cardiovascular Medicine, Oregon Health & Science University, UHN62, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
Journal of Cardiovascular Computed Tomography
|February 5, 2010
Summary
Cardiovascular computed tomography (CT) accurately evaluates coronary artery disease. New methods allow CT to assess myocardial perfusion, offering a complete view of coronary anatomy and function.
Area of Science:
- Cardiovascular imaging
- Radiology
- Cardiac diagnostics
Background:
- Cardiovascular computed tomography (CT) is a validated tool for assessing coronary artery atherosclerosis and stenosis.
- Diagnostic accuracy of CT angiography is comparable to conventional coronary angiography.
- CT angiography currently does not assess the functional significance of coronary lesions.
Purpose of the Study:
- To review the principles, technical considerations, and potential of stress myocardial perfusion imaging using CT.
- To highlight the emerging capability of CT in evaluating both coronary anatomy and physiology.
Main Methods:
- Review of existing literature on cardiovascular CT and myocardial perfusion imaging.
- Discussion of technical aspects and principles of stress myocardial perfusion imaging with CT.
Main Results:
- Cardiovascular CT demonstrates high diagnostic accuracy for coronary artery disease.
- Myocardial perfusion imaging with CT is emerging as a feasible technique.
- CT offers the potential for a comprehensive assessment of coronary anatomy and physiology.
Conclusions:
- Stress myocardial perfusion imaging with CT is a promising development.
- CT may provide a single-examination solution for evaluating both coronary anatomy and function.
- Further research and validation are ongoing for CT-based myocardial perfusion imaging.
Related Concept Videos
01:28Imaging Studies for Cardiovascular System V: CT
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
01:21Imaging Studies for Cardiovascular System IV: CMRI
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
01:30Acute Coronary Syndrome III: Diagnostic Studies
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
01:25Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
01:25Imaging Studies II: Positron Emission Tomography and Scintigraphy
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Fundamental Principles of PET
01:20Imaging Studies for Cardiovascular System II:Types of Echocardiography
Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...