Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chronic multifocal demyelinating neuropathy simulating motor neuron disease.

P Di Bella1, F Logullo, L Dionisi

  • 1Istituto delle Molattie del Sistema Nervoso, Università di Ancona.

Italian Journal of Neurological Sciences
|February 1, 1991
PubMed
Summary

A patient initially diagnosed with motor neuron disease was found to have a treatable polyneuropathy. Electrophysiology revealed unusual conduction blocks, crucial for accurate diagnosis and management.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lacosamide in monotherapy in BTRE (brain tumor-related epilepsy): results from an Italian multicenter retrospective study.

Journal of neuro-oncology·2022
Same author

Pathology without microscope: From a projection screen to a virtual slide.

Pathology, research and practice·2020
Same author

Mitochondrial DNA haplogroups may influence Fabry disease phenotype.

Neuroscience letters·2016
Same author

Efficacy and safety of cannabinoid oromucosal spray for multiple sclerosis spasticity.

Journal of neurology, neurosurgery, and psychiatry·2016
Same author

The Frequencies of Different Inborn Errors of Metabolism in Adult Metabolic Centres: Report from the SSIEM Adult Metabolic Physicians Group.

JIMD reports·2015
Same author

Targeting prostate-specific membrane antigen for personalized therapies in prostate cancer: morphologic and molecular backgrounds and future promises.

Journal of biological regulators and homeostatic agents·2015

Area of Science:

  • Neurology
  • Neurophysiology

Background:

  • Chronic acquired polyneuropathy can mimic motor neuron diseases.
  • Accurate diagnosis is essential for appropriate patient management.

Observation:

  • A patient presented with a chronic, primarily motor polyneuropathy.
  • Initial clinical presentation suggested amyotrophic lateral sclerosis (ALS).

Findings:

  • Electrophysiological studies identified multifocal, predominantly proximal conduction blocks.
  • These blocks occurred at non-compressive sites, distinguishing it from typical neuropathies.

Implications:

  • This case highlights the importance of electrophysiological assessment in differentiating polyneuropathy from motor neuron disease.

Related Experiment Videos

  • Early and accurate diagnosis of this treatable polyneuropathy is critical for patient outcomes.