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Updated: Jun 16, 2026

Culture and Imaging of Human Nasal Epithelial Organoids
Published on: December 17, 2021
Diagnostic imaging of the pediatric nasal cavity and paranasal sinuses
1Department of Radiology and Neuroradiology, Vittore Buzzi Childrens Hospital, Istituti Clinici di Perfezionamento, Milan, Italy. ftriulzi@icp.mi.it
Insights
Pediatric rhinosinusitis is common, but congenital malformations and neoplasms also affect nasal cavities and paranasal sinuses. Advanced imaging like MDCT and MRI aid diagnosis of these diverse pediatric nasal and sinus diseases.
Area of Science:
- Pediatric Radiology
- Otolaryngology
- Medical Imaging
Background:
- Most childhood nasal and paranasal sinus (PNS) diseases are inflammatory, with rhinosinusitis being frequent in acute and chronic forms.
- Congenital malformations and neoplasms can also affect the pediatric nasal cavity (NC) and PNS.
- Accurate diagnosis is crucial for effective management of these diverse conditions.
Purpose of the Study:
- To review the diagnostic role of modern radiological techniques in pediatric NC and PNS diseases.
- To highlight the characteristic features of MDCT and MRI in evaluating common and rare pediatric conditions.
- To aid in the differential diagnosis of inflammatory, neoplastic, and congenital diseases affecting the pediatric nasal and sinus complex.
Main Methods:
- Review of multidetector computerized tomography (MDCT) and magnetic resonance imaging (MRI) findings.
- Analysis of characteristic imaging features for various pediatric nasal and sinus pathologies.
- Comparison of MDCT and MRI utility in diagnosing inflammatory, neoplastic, and congenital conditions.
Main Results:
- MDCT and MRI are essential for diagnosing chronic or complicated inflammatory processes in pediatric NC and PNS.
- These imaging modalities assist in differentiating common inflammatory conditions from less frequent congenital malformations and neoplasms.
- Characteristic imaging features help delineate the extent and nature of diseases within the nasal cavity and paranasal sinuses.
Conclusions:
- Modern imaging techniques like MDCT and MRI are indispensable for the comprehensive evaluation of pediatric nasal and paranasal sinus diseases.
- These radiological tools facilitate accurate diagnosis and differential diagnosis, encompassing inflammatory, neoplastic, and congenital pathologies.
- Understanding the specific features on MDCT and MRI is key to managing pediatric patients with nasal and sinus disorders.
Abstract:
The vast majority of nasal and paranasal sinuses (PNS) diseases in childhood are of inflammatory origin. In particular, during the early rapid development of PNS rhinosinusitis are exceedingly frequent in both acute and chronic forms. However other diseases such as primarily congenital malformation, but also neoplasms can affect the nasal cavity (NC) and PNS during pediatric age. Modern radiological techniques such as multidetector computerized tomography (MDCT) or magnetic resonance imaging (MRI) are becoming of greater importance in the diagnosis of chronic or complicated inflammatory processes of NC and PNS and in the differential diagnosis with the other less frequent diseases. The characteristic features of MDCT and MRI and their diagnostic role in the more frequent pediatric inflammatory, neoplastic and congenital diseases of NC and PNS are reviewed.
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