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Updated: Jun 16, 2026

Controllable Nucleation of Cavitation from Plasmonic Gold Nanoparticles for Enhancing High Intensity Focused Ultrasound Applications
Published on: October 5, 2018
High-intensity focused ultrasound: ready for primetime
Kyle O Rove1, Kathryn F Sullivan, E David Crawford
1Division of Urology, University of Colorado Anschutz Medical Campus, 12631 East 17th Avenue, Mailstop C302, Aurora, CO 80045, USA.
High-Intensity Focused Ultrasound (HIFU) offers a novel experimental therapy for prostate cancer (CaP), a leading cause of cancer death. This review details HIFU
Area of Science:
- Oncology
- Urology
- Medical Technology
Background:
- Prostate cancer (CaP) is a significant cause of mortality in the United States.
- The incidence of CaP remains constant, but age-adjusted death rates have declined.
- There is a need for effective and innovative treatment options for prostate cancer.
Purpose of the Study:
- To review the current literature on High-Intensity Focused Ultrasound (HIFU) as an experimental therapy for prostate cancer.
- To discuss the mechanism of action, patient selection, efficacy, and complications of HIFU.
- To explore the future developments and follow-up protocols for HIFU treatment in prostate cancer.
Main Methods:
- Literature review of experimental therapy for HIFU in prostate cancer.
- Discussion of HIFU technique, mechanism of action, and patient selection criteria.
- Analysis of current efficacy studies, complications, and follow-up data.
Main Results:
- HIFU is an experimental therapy with a discussed mechanism of action and patient selection criteria.
- Current efficacy studies, complications, and follow-up data are presented.
- The review covers the technical aspects and clinical application of HIFU for prostate cancer.
Conclusions:
- HIFU represents a developing experimental treatment modality for prostate cancer.
- Further research and clinical studies are needed to establish the full potential and safety of HIFU.
- The review provides a comprehensive overview of HIFU for prostate cancer, including its current status and future prospects.
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