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Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

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Pseudophakic eye globe disruption.

Ilaria Motolese¹, Paolo Alfonso Motolese, Paolo Frezzotti

¹Department of Ophthalmology, University of Siena, Siena, Italy. ilaria.motolese@libero.it

European Journal of Ophthalmology

|February 16, 2010

Summary

Major ocular trauma with scleral rupture can lead to poor outcomes. However, advanced surgical techniques and delayed intervention improved visual acuity to 0.9 in a severe case, challenging traditional urgent treatment protocols.

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Area of Science:

Ophthalmology
Trauma Surgery
Ocular Trauma

Background:

Scleral rupture from blunt force trauma historically led to poor visual outcomes.
Refined surgical techniques, antibiotics, and corticosteroids have shifted treatment paradigms towards more conservative approaches.
Major ruptures often resulted in eye atrophy or subatrophy.

Observation:

A 63-year-old male presented with severe left ocular trauma and subconjunctival intraocular lens dislocation.
Surgical intervention was delayed by 3 weeks post-trauma to allow for hematoma resolution and patient stabilization.
A significant palpebral-frontal hematoma initially obscured the globe, necessitating its reabsorption before surgery.

Findings:

The patient achieved a best-corrected visual acuity of 0.9 one year post-surgery.
Improvements in surgical techniques have enabled better management of severe scleral ruptures.
The case highlights the potential for successful outcomes even in major ocular trauma.

Implications:

The necessity of urgent surgical intervention for major scleral ruptures requires reevaluation.
Delayed surgical treatment, coupled with advanced techniques, can yield favorable visual results.
Optimizing treatment strategies, both technically and organizationally, is crucial for managing severe ocular trauma effectively.