Related Experiment Video
Updated: Jun 16, 2026

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
Published on: August 25, 2021
Pseudophakic eye globe disruption
Ilaria Motolese1, Paolo Alfonso Motolese, Paolo Frezzotti
1Department of Ophthalmology, University of Siena, Siena, Italy. ilaria.motolese@libero.it
Purpose:
Scleral rupture due to bulb bursting can result from a heavy contusion. Owing to refined surgical techniques and the use of antibiotics and cortisone-based medication, more conservative concepts have followed. In major ruptures, the results were almost always very poor, with atrophy or subatrophy of the eyes.
Methods:
A 63-year-old man with major left ocular trauma and intraocular lens dislocation in the subconjunctival area was referred to the authors for clinical and surgical evaluation.
Results:
Surgery was performed 3 weeks after the trauma to allow for improvement in the patient's condition. The reabsorption of a palpebral-frontal hematoma, which made bulb exploration almost impossible, was fundamental in order to proceed. After 1 year, the best-corrected visual acuity was 0.9. In fact, great improvements in surgical techniques in recent years have allowed us to consider the problem of major rupture in a new way, both technically and from an organizational point of view.
Conclusions:
In terms of organization, the concept of urgent surgical procedures must be reevaluated, because besides traumatic damage, incomplete surgical measures may result. This makes all treatment useless, in both barely equipped and highly specialized centers.
More Related Videos
Related Concept Videos
Glaucoma: Overview
Photoreceptors and Visual Pathways
Angle Closure Glaucoma: Treatment
Focusing of Light in the Eye

