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Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

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Cystic fibrosis presenting with dermatitis.

Kurt S Wenk¹, Kristen B Higgins, Kenneth E Greer

¹Department of Dermatology, University of Virginia Health System, Charlottesville, USA. kswenk@gmail.com

Archives of Dermatology

|February 17, 2010

Summary

Cystic fibrosis can manifest as dermatitis in infants due to malnutrition. Addressing deficiencies in zinc, essential fatty acids, and protein is crucial for managing this rare presentation.

Area of Science:

Pediatrics
Dermatology
Genetics

Background:

Cystic fibrosis (CF) typically presents with pulmonary and pancreatic issues.
Dermatitis is an atypical initial symptom of CF, often linked to nutritional deficits.

Observation:

A 3-month-old infant with CF presented with dermatitis and protein-energy malnutrition.
Laboratory reviews suggest zinc, essential fatty acid, and protein deficiencies contribute to CF-related rashes.

Findings:

Nutritional deficiencies, including zinc, essential fatty acids, and protein, are implicated in cystic fibrosis dermatitis.
Multiple interacting deficiencies may influence the development of the rash.

Implications:

Considering cystic fibrosis in infants with rash and malnutrition is vital due to diagnostic delays and associated risks.

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Early diagnosis and nutritional support can improve outcomes for infants with CF presenting with dermatitis.