Jove
Visualize
Contact Us

Related Concept Videos

Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
Genetic Lingo01:11

Genetic Lingo

Overview
Personality Disorders: Dependent and Obsessive-Compulsive01:24

Personality Disorders: Dependent and Obsessive-Compulsive

Dependent personality disorder and obsessive-compulsive personality disorder are two separate psychological conditions that influence behavior, relationships, and overall life functioning. Though both involve maladaptive behaviors, their core characteristics and motivations differ significantly.
 Dependent Personality Disorder
Dependent personality disorder is characterized by an excessive reliance on others to manage various aspects of life. Individuals with this disorder often struggle with...
Incomplete Dominance01:43

Incomplete Dominance

Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A study of alcohol dependence in obsessive-compulsive disorder.

Journal of psychiatric research·2026
Same author

Early life adversity, inhibitory control, and behavioral dysregulation among individuals with OCD.

Psychiatry research·2026
Same author

Subjective sleep disruption, coping, and anxiety and related symptoms in the perinatal period: findings from a longitudinal study.

Sleep·2026
Same author

Perinatal obsessive-compulsive symptoms and maternal-infant bonding: A longitudinal examination of depression and relationship quality.

Archives of women's mental health·2026
Same author

Onset and exacerbation of obsessive-compulsive disorder in the perinatal period.

Archives of women's mental health·2026
Same author

Rare coding mutations identify 36 large-effect risk genes in obsessive-compulsive disorder and chronic tic disorders.

medRxiv : the preprint server for health sciences·2025
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 16, 2026

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
09:29

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

Genetics of obsessive-compulsive disorder.

Gerald Nestadt1, Marco Grados, Jack F Samuels

  • 1Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Johns Hopkins Hospital, Meyer 113, 600 North Wolfe Street, Baltimore, MD 21287, USA. gnestadt@jhmi.edu

The Psychiatric Clinics of North America
|February 18, 2010
PubMed
Summary

Obsessive-compulsive disorder (OCD) is a common condition with genetic and environmental influences. Further research is needed to pinpoint the exact genetic and environmental causes of OCD.

More Related Videos

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice
06:50

Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice

Published on: December 24, 2013

Related Experiment Videos

Last Updated: Jun 16, 2026

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
09:29

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice
06:50

Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice

Published on: December 24, 2013

Area of Science:

  • Psychiatry and Genetics

Background:

  • Obsessive-compulsive disorder (OCD) is a prevalent and disabling mental health condition.
  • It affects individuals across the lifespan, from childhood to adulthood.
  • Evidence suggests a significant genetic contribution to OCD etiology.

Purpose of the Study:

  • To review the current understanding of the causes of obsessive-compulsive disorder.
  • To highlight the interplay of genetic and environmental factors in OCD.
  • To identify areas for future research in OCD genetics.

Main Methods:

  • Review of existing literature on obsessive-compulsive disorder.
  • Analysis of genetic studies identifying potential candidate genes.
  • Consideration of environmental risk factors implicated in OCD.

Main Results:

  • OCD has a complex inheritance pattern.
  • Several genes have been implicated, but definitive causal links are not established.
  • Environmental factors likely play a role alongside genetic predisposition.

Conclusions:

  • The etiology of obsessive-compulsive disorder is multifactorial, involving both genetic and environmental influences.
  • Significant further research, particularly molecular studies, is required to elucidate the definitive causes of OCD.