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Related Concept Videos

Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Allergic Reactions02:06

Allergic Reactions

Overview
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Adrenergic Agonists: Therapeutic Uses

Adrenergic agonists have diverse therapeutic uses across various medical conditions and emergencies.
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Allergies and anaphylaxis:...
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Cardiopulmonary Resuscitation IV: Pharmacological Management01:25

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Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...
Hypersensitivities01:30

Hypersensitivities

Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
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Related Experiment Video

Updated: Jun 16, 2026

Measuring Local Anaphylaxis in Mice
07:49

Measuring Local Anaphylaxis in Mice

Published on: October 14, 2014

Action on anaphylaxis action plans.

Andrew Stewart Kemp1

  • 1Department of Allergy and Immunology and Discipline of Paediatrics and Child Health, The Children's Hospital at Westmead Clinical School, University of Sydney, New South Wales, Australia. askemp@optusnet.com.au

Journal of Paediatrics and Child Health
|February 19, 2010
PubMed
Summary
This summary is machine-generated.

Written anaphylaxis action plans are crucial for managing food-allergic children. While evidence is limited, these plans are essential for safe and effective emergency treatment of severe allergic reactions.

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Last Updated: Jun 16, 2026

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Area of Science:

  • Allergy and Immunology
  • Pediatric Medicine
  • Public Health

Background:

  • Anaphylaxis action plans are vital for children with food allergies requiring self-injectable adrenaline.
  • Current evidence supporting the efficacy of these plans is incomplete.
  • Controlled trials are unlikely due to ethical and practical considerations.

Purpose of the Study:

  • To review the current literature on the benefit of written anaphylaxis action plans for food-allergic children.
  • To highlight the importance of these plans despite limited empirical evidence.
  • To introduce new, tailored anaphylaxis action plans developed by ASCIA.

Main Methods:

  • Literature review of existing studies and guidelines on anaphylaxis management.
  • Analysis of the rationale for using action plans in clinical practice.
  • Description of newly released anaphylaxis action plans.

Main Results:

  • Evidence supporting the benefit of written anaphylaxis action plans is currently incomplete.
  • Clinical consensus and common sense support their use in managing food-allergic children.
  • New, diverse action plans have been developed to cater to specific patient needs.

Conclusions:

  • Written anaphylaxis action plans are considered essential for managing food-allergic children, particularly those prescribed self-injectable adrenaline.
  • Despite incomplete evidence, their utility is widely accepted.
  • The development of tailored action plans addresses varied patient requirements, including those without self-injectable adrenaline and those with insect allergies.