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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Related Experiment Videos

Progression in primary angle closure eyes.

Ramanjit Sihota1, Aparna Rao, Viney Gupta

  • 1Glaucoma Research Facility & Clinical Services, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. rjsihota@hotmail.com

Journal of Glaucoma
|February 19, 2010
PubMed
Summary
This summary is machine-generated.

Primary angle closure (PAC) eyes developing ocular hypertension after iridotomy often progress. Narrower angles and fluctuating intraocular pressure (IOP) indicate higher risk for developing PAC glaucoma.

Related Experiment Videos

Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Clinical Ophthalmology

Background:

  • Primary angle closure (PAC) is a condition characterized by occludable angles.
  • Iridotomy is a common intervention for PAC.
  • Long-term outcomes of PAC following iridotomy require further investigation.

Purpose of the Study:

  • To investigate the long-term clinical course of primary angle closure (PAC) eyes after laser iridotomy.
  • To identify risk factors for progression to ocular hypertension and visual field defects in PAC eyes.

Main Methods:

  • Seventy-two PAC eyes without initial ocular hypertension underwent laser iridotomy.
  • Intraocular pressure (IOP) and standard achromatic perimetry were monitored for at least 4 years.
  • Statistical analysis was performed to assess changes and identify predictive factors.

Main Results:

  • 26 eyes (36%) developed ocular hypertension requiring medication within the follow-up period.
  • 8 eyes (11%) developed visual field defects, indicating progression to PAC glaucoma.
  • Narrower baseline angles (≤10 degrees), higher baseline visual field indices (MD, PSD), and greater IOP fluctuations were associated with progression.

Conclusions:

  • A significant proportion of PAC eyes treated with iridotomy can develop ocular hypertension and potentially PAC glaucoma.
  • Eyes with very narrow angles and significant IOP fluctuations are at higher risk.
  • Long-term monitoring is crucial for early detection and management of progression in PAC.