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Published on: September 26, 2018
Current cardiovascular risk management patterns with special focus on lipid lowering in daily practice in Switzerland
Andres Jaussi1, Georg Noll, Bernhard Meier
1University Hospital of Lausanne, Medical Policlinic, CHUV Lausanne, Lausanne, Switzerland. andres.jaussi@vtx.ch
Insights
Physicians struggle to meet guideline targets for LDL cholesterol and blood pressure in high-risk patients. Intensified medical education and guideline implementation are crucial for improving cardiovascular disease management.
Area of Science:
- Cardiology
- Preventive Medicine
- Clinical Practice Research
Background:
- A significant gap exists between recommended and actual LDL cholesterol (LDL-C) and blood pressure (BP) control in clinical practice.
- Physician estimates of patient risk may differ from objective assessments.
Purpose of the Study:
- To assess cardiovascular disease risk profiles and management of lipid-lowering and BP-lowering therapies in daily practice.
- To evaluate goal attainment rates for LDL-C and BP in high-risk patients.
Main Methods:
- Prospective cross-sectional survey involving 635 general practitioners and 23,892 patients.
- Cardiovascular risk assessment using PROCAM score and evaluation of LDL-C and BP levels.
- Phase 2 focused on high-risk patients not achieving LDL-C goals (< 2.6 mmol/l).
Main Results:
- 40% of patients were identified as high-risk, exceeding physician estimates (27%).
- Goal attainment was higher for BP (62%) than LDL-C (37%) in high-risk patients; only 25% achieved both.
- Among high-risk patients not at goal, 32% achieved LDL-C goal after 17 weeks, with optimal strategies used in only 22%.
Conclusions:
- Despite intensive treatment, the majority of high-risk patients remain inadequately controlled.
- Intensified medical education is needed to improve adherence to guidelines.
- Better implementation of international and Swiss guidelines could enhance LDL-C and BP goal achievement.
Background:
There may be a considerable gap between LDL cholesterol (LDL-C) and blood pressure (BP) goal values recommended by the guidelines and results achieved in daily practice.
Design:
Prospective cross-sectional survey of cardiovascular disease risk profiles and management with focus on lipid lowering and BP lowering in clinical practice.
Methods:
In phase 1, the cardiovascular risk of patients with known lipid profile visiting their general practitioner was anonymously assessed in accordance to the PROCAM-score. In phase 2, high-risk patients who did not achieve LDL-C goal less than 2.6 mmol/l in phase 1 could be further documented.
Results:
Six hundred thirty-five general practitioners collected the data of 23 892 patients with known lipid profile. Forty percent were high-risk patients (diabetes mellitus or coronary heart disease or PROCAM-score >20%), compared with 27% estimated by the physicians. Goal attainment rate was almost double for BP than for LDL-C in high-risk patients (62 vs. 37%). Both goals were attained by 25%. LDL-C values in phase 1 and 2 were available for 3097 high-risk patients not at LDL-C goal in phase 1; 32% of patients achieved LDL-C goal of less than 2.6 mmol/l after a mean of 17 weeks. The most successful strategies for LDL-C reduction were implemented in only 22% of the high-risk patients.
Conclusion:
Although patients at high cardiovascular risk were treated more intensively than low or medium risk patients, the majority remained insufficiently controlled, which is an incentive for intensified medical education. Adequate implementation of Swiss and International guidelines would expectedly contribute to improved achievement of LDL-C and BP goal values in daily practice.
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