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Microfluidic Fabrication of Core-Shell Microcapsules carrying Human Pluripotent Stem Cell Spheroids
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Microfluidic Fabrication of Core-Shell Microcapsules carrying Human Pluripotent Stem Cell Spheroids

Published on: October 13, 2021

Organic-inorganic double shell composite microcapsules.

Yue Long1, Brian Vincent, David York

  • 1School of Chemistry, University of Birmingham, Edgbaston, Birmingham, UKB15 2TT.

Chemical Communications (Cambridge, England)
|February 24, 2010
PubMed
Summary
This summary is machine-generated.

Researchers developed new double shell composite microcapsules. These microcapsules feature a melamine formaldehyde polymer inner shell and a calcium carbonate nanoparticle outer shell for advanced material applications.

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Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Nanotechnology

Background:

  • Composite microcapsules offer unique properties for various applications.
  • Developing microcapsules with distinct inner and outer shells presents fabrication challenges.

Purpose of the Study:

  • To synthesize novel double shell composite microcapsules.
  • To characterize the structure and properties of the fabricated microcapsules.

Main Methods:

  • Utilized in situ polymerization for melamine formaldehyde (MF) inner shell formation.
  • Employed a method to create a ripened calcium carbonate (CaCO3) nanoparticle outer shell.
  • Integrated MF polymer shell formation within pre-existing CaCO3 nanoparticle microcapsule walls.

Main Results:

  • Successfully prepared double shell composite microcapsules with MF inner and CaCO3 nanoparticle outer shells.
  • Demonstrated the feasibility of forming the MF polymer shell within the CaCO3 nanoparticle wall.
  • Characterized the resulting composite structure, highlighting the double shell integrity.

Conclusions:

  • The in situ polymerization method is effective for creating novel MF/CaCO3 double shell composite microcapsules.
  • These microcapsules hold potential for applications requiring tailored encapsulation and controlled release.
  • Further research can explore the functionalization and specific applications of these advanced composite materials.