Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Feasibility and perioperative safety of robotic liver resection using the da Vinci SP system: early single-center case series.

Surgical endoscopy·2026
Same author

Frequency-Based Inference of Ventricular Tachycardia Circuit Dimensionality and Isthmus Depth in Post-Myocarditis Substrate.

JACC. Clinical electrophysiology·2026
Same author

Multimodal intervention benefits: Responder analysis of J-MINT PRIME Kanagawa trial.

Archives of gerontology and geriatrics·2026
Same author

Patchy Earliest Activation on Near-Field Annotation Mapping: A Pitfall in Ablation of Premature Ventricular Contractions Originating From the Right Ventricular Outflow Tract.

Journal of arrhythmia·2026
Same author

A poorly reactogenic lipid nanoparticle-mRNA vaccine unveils an innate immune pathway for adverse reactions.

NPJ vaccines·2026
Same author

[Recent Review Article in RPT: PET Detectors with Depth-of-interaction and Time-of-flight Capabilities].

Igaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics·2026
Same journal

The Prognostic Value of <sup>68</sup>Ga-PSMA and <sup>18</sup>F-FDG PET/CT in Metastatic Castration-Resistant Prostate Cancer Treated with <sup>177</sup>Lu-EB-PSMA.

Annals of nuclear medicine·2026
Same journal

Atomic degradation: chemical design strategies and immunotherapeutic mechanisms of radio-PROTACs.

Annals of nuclear medicine·2026
Same journal

Impact of biguanide therapy on hepatic <sup>18</sup>F-fluorodeoxyglucose-positron emission tomography quantitative parameters in patients with diabetes: a dynamic positron emission tomography study.

Annals of nuclear medicine·2026
Same journal

Dual-time-point 68Ga-FAPI PET/CT in gastrointestinal malignancies: head-to-head comparison with 18 F-FDG for lesion detection and patient-level assessment.

Annals of nuclear medicine·2026
Same journal

Bloodpool SPECT/CT offers enhanced sensitivity for the diagnosis of frozen shoulder.

Annals of nuclear medicine·2026
Same journal

Adsorption treatment of <sup>177</sup>Lu radioactive wastewater with <sup>177m</sup>Lu impurity: batch versus column methods.

Annals of nuclear medicine·2026
See all related articles

Related Experiment Video

Updated: Jun 15, 2026

Automated Radiochemical Synthesis of [18F]3F4AP: A Novel PET Tracer for Imaging Demyelinating Diseases
11:03

Automated Radiochemical Synthesis of [18F]3F4AP: A Novel PET Tracer for Imaging Demyelinating Diseases

Published on: May 29, 2017

Point-like radioactive source with multiple absorber capsules for evaluating PET scanners.

Tomoyuki Hasegawa1, Eiji Yoshida, Yasushi Sato

  • 1School of Allied Health Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara, Kanagawa, 228-8555, Japan. hasegawa@kitasato-u.ac.jp

Annals of Nuclear Medicine
|February 24, 2010
PubMed
Summary
This summary is machine-generated.

This study introduces a novel point-like radioactive source designed to accurately evaluate Positron Emission Tomography (PET) scanner performance. The new method eliminates uncertainties from absorber materials, enabling reliable sensitivity and uncertainty measurements.

More Related Videos

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space
14:19

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space

Published on: February 1, 2016

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera
06:28

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Published on: January 30, 2020

Related Experiment Videos

Last Updated: Jun 15, 2026

Automated Radiochemical Synthesis of [18F]3F4AP: A Novel PET Tracer for Imaging Demyelinating Diseases
11:03

Automated Radiochemical Synthesis of [18F]3F4AP: A Novel PET Tracer for Imaging Demyelinating Diseases

Published on: May 29, 2017

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space
14:19

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space

Published on: February 1, 2016

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera
06:28

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Published on: January 30, 2020

Area of Science:

  • Nuclear Instrumentation
  • Medical Imaging Physics

Background:

  • Positron Emission Tomography (PET) scanners require radioactive sources for performance evaluation.
  • Absorber materials in radioactive sources introduce attenuation and scattering, causing uncertainty in measurements.
  • Existing methods struggle to isolate the true performance characteristics of PET scanners from source-induced effects.

Purpose of the Study:

  • To develop a point-like radioactive source that allows for performance evaluation independent of absorber material effects.
  • To mitigate uncertainties in sensitivity and uncertainty measurements of PET scanners.

Main Methods:

  • A point-like radioactive source was designed with a spherical radioactive component and multiple cylindrical aluminum absorber capsules of varying sizes.
  • Data were acquired using different total absorber thicknesses.
  • An extrapolation technique was employed to eliminate the influence of the source absorbers on the measurements.

Main Results:

  • The proposed point-like radioactive source successfully enabled the evaluation of sensitivity and uncertainty in radioactivity measurements.
  • The extrapolation technique effectively removed the confounding effects of the source absorbers.

Conclusions:

  • The developed point-like radioactive source provides a robust method for assessing PET scanner performance.
  • This approach ensures that performance evaluations are independent of scatter and attenuation caused by the source's absorber materials.