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A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
Published on: October 15, 2013
Integrated extended-nano chemical systems on a chip
Takehiko Tsukahara1, Kazuma Mawatari, Takehiko Kitamori
1The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo 113-8656, Japan.
Chemical Society Reviews
|February 25, 2010
Summary
Researchers explore the emerging extended-nano space (10-100 nm), bridging microfluidics and nanotechnology. New fluidic and chemical phenomena are discovered, enabling unique operations for future applications.
Area of Science:
- Fluidics and chemistry in the extended-nano space (10-100 nm).
- Interdisciplinary research bridging microfluidics and nanotechnology.
Background:
- Microfluidics has enabled rapid, efficient applications in analytical and chemical synthesis.
- Conventional nanotechnology and microtechnology lack tools for the intermediate extended-nano space.
Purpose of the Study:
- To review basic research in the extended-nano space.
- To survey fundamental technologies and unique liquid properties.
- To introduce novel chemical operations and future perspectives.
Main Methods:
- Development of basic methodologies for extended-nano fluidics and chemistry.
- Investigation of phenomena in the transient space between single molecules and bulk phases.
Main Results:
- Discovery of specific fluidic and chemical phenomena in the extended-nano space.
- Application of these phenomena to unique chemical operations like concentration and ion selection.
- Establishment of new research fields distinct from microspace research.
Conclusions:
- The extended-nano space presents unique challenges and opportunities.
- Fundamental research is crucial for developing tools and understanding properties.
- Emerging applications in chemical operations show significant future potential.
