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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
[Postsurgical pituitary apoplexy. Report of two cases].
J González-Tortosa1, M Poza-Poza
1Servicio de Neurocirugía, Hospital Universitario Virgen de la Arrixaca, Murcia.
Neurocirugia (Asturias, Spain)
|February 27, 2010
Summary
Two patients with large pituitary macroadenomas experienced tumor swelling and neurological decline after surgery. This study reviews potential causes and prevention strategies for this rare post-operative complication.
Area of Science:
- Neurosurgery
- Endocrinology
- Pathology
Context:
- Pituitary macroadenomas are tumors of the pituitary gland.
- Transsphenoidal partial resection is a common surgical approach.
- Post-operative complications can significantly impact patient outcomes.
Purpose:
- To report and analyze two cases of pituitary macroadenoma regrowth after transsphenoidal surgery.
- To investigate the pathophysiological mechanisms behind tumor necrosis and swelling.
- To identify potential strategies for preventing this adverse event.
Summary:
- Two patients with large pituitary macroadenomas developed post-operative tumor swelling and necrosis after partial transsphenoidal resection.
- This led to increased tumor volume, compression of adjacent structures, and neurological deterioration.
- Literature review was conducted to explore underlying mechanisms and preventive measures.
Impact:
- Highlights a rare but serious complication following pituitary macroadenoma surgery.
- Informs neurosurgical and endocrine practices regarding potential risks.
- Contributes to understanding tumor behavior and management post-resection.