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Updated: Jun 15, 2026

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus
13:41

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus

Published on: March 8, 2012

[How did I contract human Papillomavirus (HPV)?].

N Gavillon1, H Vervaet, E Derniaux

  • 1Service de gynécologie-obstétrique, institut Alix-de-Champagne, CHU de Reims, 45, rue Cognacq-Jay, 51092 Reims cedex, France.

Gynecologie, Obstetrique & Fertilite
|March 2, 2010
PubMed
Summary
This summary is machine-generated.

Human Papillomavirus (HPV) is a common infection with over 120 genotypes. Understanding its varied transmission routes, beyond sexual contact, is crucial for effective prevention strategies.

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RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
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RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma

Published on: March 11, 2014

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Last Updated: Jun 15, 2026

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus
13:41

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus

Published on: March 8, 2012

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
10:26

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma

Published on: March 11, 2014

Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Context:

  • Human Papillomavirus (HPV) comprises over 120 genotypes with tropism for skin and mucous membranes.
  • HPV infections are a global health concern, with genital HPV being the most common sexually transmitted infection.
  • Approximately 75% of women encounter HPV in their lifetime.

Purpose:

  • To explore the diverse transmission routes of Human Papillomavirus (HPV).
  • To investigate potential non-sexual transmission pathways of HPV.
  • To highlight the need for enhanced knowledge in HPV transmission for improved prevention.

Summary:

  • HPV is typically transmitted via skin-to-skin contact, predominantly during penetrative sexual activity.
  • Non-penetrative genital contact can transmit HPV, though less commonly than intercourse.
  • Transmission can occur during delivery, with vaginal birth posing a higher risk than Cesarean sections, though neither offers complete protection.
  • Vertical transmission in utero is suspected but lacks definitive evidence.
  • While HPV DNA is found on fomites, transmission via inanimate objects is not established.

Impact:

  • Clarifying HPV transmission routes, including perinatal and potential environmental exposure, is essential for developing more effective public health interventions.
  • This knowledge can inform targeted prevention strategies for various populations, including those not typically considered at high risk.
  • Further research into less understood transmission pathways can lead to a comprehensive understanding of HPV epidemiology.