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Updated: Jun 15, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
Hearing loss in cystic fibrosis
Luciana M N Martins1, Paulo A M Camargos, Helena M G Becker
1Department of Otorhinolaryngology, Medical School, Federal University of Minas, Gerais, Brazil.
Cystic fibrosis patients have a high prevalence of hearing loss. While aminoglycoside use was common, it was not statistically linked to hearing impairment in this study.
Area of Science:
- Otolaryngology
- Genetics
- Pediatrics
Background:
- Cystic fibrosis (CF) is a genetic disorder affecting multiple organs.
- Sensorineural hearing loss (SNHL) is a potential complication in CF patients.
- Aminoglycoside antibiotics are frequently used in CF management but can be ototoxic.
Purpose of the Study:
- To determine the prevalence of hearing loss in pediatric CF patients.
- To investigate the association between aminoglycoside use and hearing loss in CF.
- To evaluate the utility of distortion product otoacoustic emissions (DPOAE) for SNHL screening in CF.
Main Methods:
- A descriptive study involving 120 CF patients (5 months to 18 years).
- Assessment included questionnaires, pure tone audiometry, and DPOAE testing.
- Aminoglycoside exposure was determined via medical chart review.
Main Results:
- Audiometry revealed a 4-11% prevalence of SNHL.
- 89.2% of patients passed DPOAE testing.
- No statistically significant correlation was found between aminoglycoside use and hearing loss (p=0.48).
Conclusions:
- CF patients exhibit a high prevalence of hearing loss, necessitating regular audiological monitoring.
- DPOAE testing is a viable method for assessing SNHL in this population.
- Aminoglycoside use is not the sole factor contributing to hearing loss in cystic fibrosis.
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