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Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

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Related Experiment Video

Updated: Jun 15, 2026

Murine Full-thickness Skin Transplantation
07:59

Murine Full-thickness Skin Transplantation

Published on: January 2, 2017

Bridge to transplantation: current outcomes.

Sanjeev Aggarwal1, Francis D Pagani

  • 1Division of Thoracic and Cardiovascular Surgery, University of Louisville, Louisville, Kentucky, USA.

Journal of Cardiac Surgery
|March 6, 2010
PubMed
Summary
This summary is machine-generated.

Implantable ventricular assist devices have evolved, with new continuous-flow pumps improving durability and reducing adverse events. This advancement expands their use in treating advanced heart failure as a bridge to transplantation.

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Published on: November 7, 2020

Area of Science:

  • Cardiology
  • Biomedical Engineering

Background:

  • Advanced, decompensated heart failure requires advanced treatment options.
  • Heart transplantation is a definitive therapy for end-stage heart failure.

Purpose of the Study:

  • To review the evolution of implantable ventricular assist devices (VADs) for bridge to transplant therapy.
  • To highlight advancements in VAD technology and management.

Main Methods:

  • Review of recent literature on VADs for bridge to transplant.
  • Analysis of improvements in device design and adverse event management.

Main Results:

  • Significant evolution in VAD therapy over the past decade.
  • Introduction of smaller, more durable continuous-flow rotary pumps.
  • Reduced incidence of serious adverse events with newer VADs.

Conclusions:

  • Modern VADs have expanded treatment options for advanced heart failure patients awaiting transplantation.
  • Improved VAD technology enhances patient outcomes and therapy accessibility.