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Updated: Jun 15, 2026

19:53
Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer
Published on: March 1, 2015
An approach to bilateral facial paralysis
Alex C S Woollard1, Douglas H Harrison, Adriaan O Grobbelaar
1The Royal Free Hospital, Pond Street, Hampstead, London NW32QG, United Kingdom. alex.woollard@googlemail.com
Summary
Möbius syndrome treatment using functional free muscle transfers showed significant smile improvement in 20 cases. Single-stage bilateral reanimation with Latissimus dorsi muscles yielded better results in younger patients.
Area of Science:
- Neurology
- Plastic Surgery
- Pediatric Surgery
Background:
- Möbius syndrome involves congenital paralysis of the Facial and Abducens nerves.
- Functional free muscle transfers are the primary treatment for Möbius syndrome.
- This study presents the largest published series of Möbius reanimation to date.
Purpose of the Study:
- To evaluate the outcomes of functional free muscle transfers in 20 patients with Möbius syndrome.
- To describe the evolution of surgical technique for Möbius reanimation.
- To assess the impact of age on smile reanimation outcomes.
Main Methods:
- A retrospective review of 20 consecutive cases of Möbius reanimation.
- Surgical technique involves a single-stage bilateral procedure using segmental Latissimus dorsi muscles.
- Muscles are innervated by the masseteric branch of the Trigeminal nerve.
- Outcomes were assessed by the senior surgeon and an independent panel.
Main Results:
- All 20 cases demonstrated significant improvement in facial animation.
- The preferred surgical approach evolved to a single-stage bilateral Latissimus dorsi transfer.
- A more spontaneous smile was observed in patients under ten years of age.
Conclusions:
- Functional free muscle transfer is an effective treatment for Möbius syndrome.
- Single-stage bilateral Latissimus dorsi reanimation provides significant functional improvement.
- Age is a factor influencing the quality of the achieved smile in pediatric patients.
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