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Hybrid Microdrive System with Recoverable Opto-Silicon Probe and Tetrode for Dual-Site High Density Recording in Freely Moving Mice

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Timing performance of the silicon PET insert probe.

A Studen¹, D Burdette, E Chesi

¹JoZef Stefan Institute, Ljubljana, Slovenia. andrej.studen@ijs.si

Radiation Protection Dosimetry

|March 11, 2010

Summary

This study addresses timing issues for a novel PET probe using silicon detectors. Simulations and measurements show reliable performance, achieving timing windows down to 20 nanoseconds for improved PET imaging.

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Area of Science:

Medical Physics
Detector Technology

Background:

Positron Emission Tomography (PET) imaging can be enhanced by probes placed near the object.
High-resistivity silicon detectors offer potential for improved PET probe timing resolution.

Purpose of the Study:

To address timing issues in a PET probe utilizing high-resistivity silicon detectors.
To evaluate the timing performance of a simplified silicon detector probe model.

Main Methods:

A simplified PET probe model with silicon detectors and VATAGP7 ASICs was exposed to annihilation photons.
Timing performance was measured using an LYSO-PMT assembly as a reference.
Results were compared against a four-part simulation including GEANT4 tracking and electronics simulation.

Main Results:

A very good agreement was found between simulation and experimental measurements.
The study indicates reliable performance of the silicon detector PET probe.
Timing windows as low as 20 nanoseconds are achievable.

Conclusions:

The developed silicon detector PET probe demonstrates reliable timing performance.
The findings support the feasibility of using this probe for enhanced PET imaging.
The validated simulation methods can guide future probe development.