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Related Concept Videos

Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Adaptive Mechanisms in Cancer Cells02:53

Adaptive Mechanisms in Cancer Cells

Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...

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Related Experiment Video

Updated: Jun 15, 2026

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
07:50

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study

Published on: April 18, 2025

Declining death rates reflect progress against cancer.

Ahmedin Jemal1, Elizabeth Ward, Michael Thun

  • 1Surveillance and Health Policy Research, American Cancer Society, Atlanta, Georgia, USA. ajemal@cancer.org

Plos One
|March 17, 2010
PubMed
Summary

Cancer death rates declined significantly in the US from 1970-2006, with notable decreases since 1990. This progress in cancer mortality is attributed to reduced tobacco use, early detection through screening, and improved treatments.

Related Experiment Videos

Last Updated: Jun 15, 2026

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
07:50

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study

Published on: April 18, 2025

Area of Science:

  • Epidemiology
  • Public Health
  • Oncology

Background:

  • The
  • war on cancer
  • initiated in 1971 has seen debated success regarding cancer mortality trends.
  • This study examines temporal trends in cancer death rates in the United States.

Purpose of the Study:

  • To analyze trends in age-standardized death rates for all cancers and 19 common cancer sites in the US from 1970-2006.

Main Methods:

  • Joinpoint regression model used to analyze age-standardized death rates (per 100,000).
  • Data spans from 1970 to 2006 for all cancers combined and 19 specific cancer sites.

Main Results:

  • All-cancer death rates in men and women showed a net decline from 1970 and 1990/1991 levels.
  • These decreases translated to hundreds of thousands of prevented cancer deaths.
  • Death rates decreased for 15 of 19 cancer sites, including lung, colorectum, prostate, and breast cancers.

Conclusions:

  • Significant progress in reducing cancer death rates is evident, whether compared to 1970 or 1990 baselines.
  • Declines since 1990 are linked to reduced tobacco use, increased cancer screening, and improved treatments.
  • Continued investment in prevention, control, healthcare access, and research is recommended to accelerate progress.