Spontaneous Progression of a Long-Standing Lamellar Macular Hole into a Full-Thickness Macular Hole

One patient with past ocular history of full thickness macular hole surgically closed in the right eye was followed with diagnostic of lamellar macular hole in the left eye since 2000. After uncomplicated cataract surgery in the left eye in March 2008, the lamellar hole spontaneously progressed to full thickness macular hole. The patient underwent pars plana vitrectomy, membrane peel and gas bubble injection, with successful closure of the macular hole and improvement in the visual acuity. Optical coherence tomography (OCT) scans through the macula were performed at the initial and follow-up visits. To the best of our knowledge, this is the first description of a long-standing stable lamellar macular hole progressing into a full thickness macular hole. The causative factors for this progression remain unclear.