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Related Concept Videos

Knee Joint01:23

Knee Joint

The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris group...
Articulations of the Vertebral Column01:28

Articulations of the Vertebral Column

In addition to being held together by the intervertebral discs, adjacent vertebrae also articulate with each other at synovial joints formed between the superior and inferior articular processes called zygapophysial joints (facet joints). These are plane joints that provide for only limited motions between the vertebrae. The orientation of the articular processes at these joints varies in different regions of the vertebral column and serves to determine the types of motions available in each...
T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
Structural Joints: Synovial Joints01:16

Structural Joints: Synovial Joints

Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...
Spinal Nerves: Plexus II01:21

Spinal Nerves: Plexus II

The plexuses of the lower body include the lumbar, sacral, and coccygeal plexuses, which innervate the abdomen, pelvis, legs, and coccygeal region. These plexuses control the transmission of sensory information and coordinate motor functions of the lower body.
The Lumbar Plexus
The lumbar plexus is situated within the lumbar region of the back and is primarily formed by the first four lumbar spinal nerves (L1 to L4). This plexus extends its branches into several nerves, including the...

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Related Experiment Video

Updated: Jun 14, 2026

Measuring Psoriasis Severity at Home
02:28

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Sacroiliac joint involvement in psoriasis.

Cahit Kaçar1, Ilhan Sezer, Hilal Kocabaş

  • 1Department of Physical Medicine Rehabilitation and Rheumatology, Akdeniz University Faculty of Medicine, Antalya, Turkey. ckacar@akdeniz.edu.tr

Rheumatology International
|April 1, 2010
PubMed
Summary

Psoriasis patients show a higher frequency of sacroiliac joint involvement, often bilateral, than previously thought. This finding challenges existing understanding of psoriatic sacroiliitis.

Related Experiment Videos

Last Updated: Jun 14, 2026

Measuring Psoriasis Severity at Home
02:28

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Area of Science:

  • Rheumatology
  • Dermatology
  • Radiology

Background:

  • Psoriasis is a chronic inflammatory disease often linked with arthritis.
  • Sacroiliac joint involvement in psoriatic arthritis is typically considered infrequent and asymmetric.

Purpose of the Study:

  • To determine the frequency and pattern of sacroiliac joint involvement in patients with psoriasis.
  • To investigate the relationship between sacroiliac involvement and clinical features of psoriasis.

Main Methods:

  • Prospective study including 133 patients with psoriasis.
  • Clinical assessment of skin, nail, and joint involvement; Psoriasis Area and Severity Index (PASI) calculation.
  • Antero-posterior pelvic X-rays graded independently by two rheumatologists and a radiologist.

Main Results:

  • Symptomatic articular involvement was present in 27% of patients.
  • Sacroiliac joint involvement was observed in 26% of patients, with over half being bilateral.
  • No significant association was found between sacroiliac joint involvement and psoriatic nail or skin disease severity.

Conclusions:

  • The study identified a higher prevalence of sacroiliac joint involvement and bilateral sacroiliitis in psoriasis patients than previously reported.
  • These findings contrast with existing literature and suggest a potentially more frequent association.
  • Further research using advanced imaging like MRI is recommended for confirmation.