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Updated: Jun 14, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
Published on: February 16, 2018
Biomimetically relevant self-condensations of C5 units derived from lysine
Rim Salame1, Edmond Gravel, Pascal Retailleau
1Université Paris-Sud, Faculté de Pharmacie, Laboratoire de Pharmacognosie associé au CNRS, UMR 8076 BioCIS, 5, rue Jean-Baptiste Clément, 92296, Châtenay-Malabry, France.
Abstract:
In various conditions, dimerization of pentanedial-derived units gives rise to interesting skeletons, which are reminiscent of alkaloids known to be biosynthesized in Nature via lysine metabolism.
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