Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 14, 2026

Optical Trapping of Nanoparticles
13:39

Optical Trapping of Nanoparticles

Published on: January 15, 2013

Calibration of optically trapped nanotools.

D M Carberry1, S H Simpson, J A Grieve

  • 1H H Wills Physics Laboratory, University of Bristol, Bristol, UK.

Nanotechnology
|April 7, 2010
PubMed
Summary

Holographically trapped nanotools enable a new force microscopy technique. Measuring tool displacement in optical traps allows inference of contact forces, crucial for nanoscale measurements.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Non-diffractive computational ghost imaging.

Optics express·2016
Same author

'Lissajous-like' trajectories in optical tweezers.

Optics express·2015
Same author

Four-directional stereo-microscopy for 3D particle tracking with real-time error evaluation.

Optics express·2014
Same author

Dynamic stereo microscopy for studying particle sedimentation.

Optics express·2014
Same author

A multi-modal stereo microscope based on a spatial light modulator.

Optics express·2013
Same author

An optically actuated surface scanning probe.

Optics express·2013

Area of Science:

  • Nanotechnology
  • Optical physics
  • Microscopy

Background:

  • Optical tweezers are used to manipulate microscopic objects.
  • Force microscopy is essential for studying nanoscale interactions.
  • Holographic trapping offers advanced control over optical forces.

Purpose of the Study:

  • To calibrate nanotools used in holographic force microscopy.
  • To investigate the stability and behavior of optically trapped nanotools.
  • To explore the influence of trap positioning on force measurements.

Main Methods:

  • Experimental calibration of a holographically trapped nanotool.
  • Measurement of nanotool displacement within optical traps.
  • Analysis of thermal motion and its effect on the device.

More Related Videos

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers
09:56

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers

Published on: August 31, 2021

Nanomanipulation of Single RNA Molecules by Optical Tweezers
06:59

Nanomanipulation of Single RNA Molecules by Optical Tweezers

Published on: August 20, 2014

Related Experiment Videos

Last Updated: Jun 14, 2026

Optical Trapping of Nanoparticles
13:39

Optical Trapping of Nanoparticles

Published on: January 15, 2013

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers
09:56

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers

Published on: August 31, 2021

Nanomanipulation of Single RNA Molecules by Optical Tweezers
06:59

Nanomanipulation of Single RNA Molecules by Optical Tweezers

Published on: August 20, 2014

Main Results:

  • Successful calibration of the nanotool for force microscopy.
  • Demonstrated independence of device behavior from minor trap position shifts.
  • Characterization of thermal motion effects on the trapped nanotool.

Conclusions:

  • Holographically trapped nanotools provide a viable method for force microscopy.
  • The calibrated device is robust against small positional variations in optical traps.
  • Understanding thermal motion is key to precise force measurements in this system.