Related Experiment Video
Updated: Jun 14, 2026
Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Microbiology and visual outcome of bleb-associated endophthalmitis
Turki A Al-Turki1, Sami Al-Shahwan, Hani S Al-Mezaine
1Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Purpose:
To identify the microbiological spectrum and visual outcome of bleb-associated endophthalmitis.
Methods:
The medical records of patients treated for bleb-associated endophthalmitis were reviewed.
Results:
Seventy-five patients were identified. Vitreous cultures were positive in 48 (64%) patients. The most common isolates were Streptococcus species in 24 (50%) eyes, gram-negative bacteria in 10 (20.8%) eyes, and Staphylococcus epidermidis in 7 (14.6%) eyes. Good visual outcome was achieved in 33 (44%) patients. On univariate analysis, shorter interval from onset of symptoms and treatment (p = .005), better initial visual acuity (p = .004), clear cornea at presentation (p = .048), isolation of less virulent organisms (p < .001), and absence of diabetes mellitus (p = .048) were significant positive predictors for good visual outcome.
Conclusions:
Bleb-associated endophthalmitis is associated with severe visual impairment. Clinical features associated with better visual outcome include early presentation, better presenting visual acuity, clear cornea at presentation, culture of a less virulent organism, and absence of diabetes mellitus.
