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Updated: Jun 14, 2026

Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models
Published on: December 3, 2019
[Demyelinating disease in human immunodeficiency virus-infected patients without severe immunodepression]
Miriam Estébanez-Muñoz1, Maria Luisa Montes, Pilar Ruiz-Seco
1Servicio de Medicina Interna, Hospital Universitario La Paz, Madrid, España. mirestmun@gmail.com
Objective:
Human immunodeficiency virus (HIV) infected patients who did not have severe immunodepression were analysed for multiple demyelinating lesions.
Methods:
Patients with a CD4 greater than 200/μL were selected after a search was made in a computerised data base.
Results:
Four patients were found, three were co-infected with hepatitis C virus (HCV), with one of them on treatment with peg-interferón α-2b and ribavirin.
Conclusion:
HIV infected patients can develop demyelinating disease without having severe immunodepression, probably favoured by other factors, such as co-infection wIth HCV.
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