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Related Experiment Video

Updated: Jun 13, 2026

Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach
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Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach

Published on: August 24, 2018

Histomorphometric analysis after maxillary sinus floor augmentation using cancellous bone-block allograft.

Gavriel Chaushu1, Marilena Vered, Ofer Mardinger

  • 1Department of Oral and Maxillofacial Surgery, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel. gabi.chaushu@gmail.com

Journal of Periodontology
|April 14, 2010
PubMed
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Cancellous bone-block allografts facilitate new bone formation for sinus augmentation in severely atrophic maxillae. This biocompatible material supports implant stability and osseointegration, proving effective for posterior maxillary ridge reconstruction.

Area of Science:

  • Oral and Maxillofacial Surgery
  • Regenerative Medicine
  • Dental Implantology

Background:

  • Sinus augmentation is crucial for dental implant placement in atrophic posterior maxillae.
  • Cancellous bone-block allografts are explored for enhancing initial implant stability in such cases.
  • Limited bone height (< or =4 mm) presents a challenge for standard augmentation procedures.

Purpose of the Study:

  • To histologically and histomorphometrically evaluate the efficacy of cancellous bone-block allografts in maxillary sinus-floor augmentation.
  • To assess new bone formation and graft integration.
  • To determine implant osseointegration rates following the procedure.

Main Methods:

  • Thirty-one patients with atrophic posterior maxillae underwent sinus augmentation with simultaneous implant placement using cancellous bone-block allografts.

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  • After a 9-month healing period, bone core samples were collected for analysis.
  • Histologic and histomorphometric examinations were performed on the collected specimens.
  • Main Results:

    • A high osseointegration rate of 94.7% (72 out of 76 implants) was achieved.
    • Histomorphometry revealed mean percentages of newly formed bone (26.1%), residual allograft (24.7%), and marrow/connective tissue (49.2%).
    • No significant differences in new bone formation were observed based on gender, age, membrane perforations, or residual alveolar bone height.

    Conclusions:

    • Cancellous bone-block allografts are biocompatible and osteoconductive.
    • The material effectively promotes new bone formation in sinus augmentations.
    • It enables successful simultaneous implant placement in extremely atrophic posterior maxillae.