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Updated: Jun 13, 2026

09:59
An “All-laser” Endothelial Transplant
Published on: July 6, 2015
[Advances in penetrating keratoplasty technique]
An-ji Wei1, Jia-xu Hong, Jian-jiang Xu
1Department of Ophthalmology, Eye Ear Nose and Throat Hospital of Fudan University, Shanghai 200031, China.
[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology
|April 15, 2010
Summary
Corneal graft failure due to rejection is common. This study analyzes new surgical techniques like femtosecond laser-shaped penetrating keratoplasty (FS-TH-PKP) to improve outcomes and reduce rejection rates.
Area of Science:
- Ophthalmology
- Transplantation Surgery
- Biomedical Engineering
Context:
- Corneal allograft rejection remains a primary cause of graft failure.
- Penetrating keratoplasty (PK) is a standard surgical treatment.
- Reducing graft rejection is a key focus in corneal transplantation.
Purpose:
- To review and analyze emerging surgical techniques for penetrating keratoplasty.
- To evaluate femtosecond laser-shaped penetrating keratoplasty (FS-TH-PKP), manual top-hat wound configuration (M-TH-PKP), and half-top-hat penetrating keratoplasty (HTH-PKP).
- To understand advancements aimed at minimizing corneal allograft rejection.
Summary:
- The study focuses on novel surgical approaches in penetrating keratoplasty.
- It examines femtosecond laser-assisted and manual "top-hat" configurations (FS-TH-PKP, M-TH-PKP) and half-top-hat techniques (HTH-PKP).
- These methods aim to enhance graft survival by addressing rejection issues.
Impact:
- Potential to reduce corneal graft failure rates.
- Offers insights into optimizing surgical strategies for better patient outcomes.
- Highlights the role of advanced technology in improving transplantation success.

