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Benzodiazepine reception in C57BL/6 and BALB/c mice depending on the type of stress factor
K S Chekina1, M A Yarkova, S B Seredenin
1V. V. Zakusov Institute of Pharmacology, Russian Academy of Medical Sciences, Moscow, Russia.
Bulletin of Experimental Biology and Medicine
|April 17, 2010
Abstract:
Specific binding of (3)H-flunitrazepam with synaptosomal membranes after exposure to open field test and "contact with predator" test was measured in C57Bl/6 and BALB/c mice. Stress-induced decrease in benzodiazepine binding after open field test was observed only in BALB/c mice and after contact with predator in both animal strains.
