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Related Experiment Video

Updated: Jun 13, 2026

Characterization of Vascular Morphology of Neovascular Age-Related Macular Degeneration by Indocyanine Green Angiography

Characterization of Vascular Morphology of Neovascular Age-Related Macular Degeneration by Indocyanine Green Angiography

Published on: August 11, 2023

Inflammatory choroidal neovascularization.

Piergiorgi Neri¹, Marta Lettieri, Cinzia Fortuna

¹The Eye Clinic-Ospedali Riuniti Umberto I-G.M. Lancisi-G. Salesi-Ancona.

Middle East African Journal of Ophthalmology

|April 21, 2010

Summary

Choroidal neovascularization (CNV) from uveitis causes vision loss. Early diagnosis with imaging and treating inflammation, potentially with anti-VEGF agents, is key for managing this severe condition.

Keywords:

Choroidal Neovascularization Choroiditis Immunosuppression Steroids Uveitis Vascular Endothelial Growth Factor

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In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model

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Published on: January 21, 2018

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Last Updated: Jun 13, 2026

Characterization of Vascular Morphology of Neovascular Age-Related Macular Degeneration by Indocyanine Green Angiography

Characterization of Vascular Morphology of Neovascular Age-Related Macular Degeneration by Indocyanine Green Angiography

Published on: August 11, 2023

In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model

In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model

Published on: January 21, 2018

Area of Science:

Ophthalmology
Immunology
Vascular Biology

Background:

Choroidal neovascularization (CNV) is a sight-threatening complication of infectious and noninfectious uveitis.
CNV often arises from posterior pole lesions, necessitating accurate diagnostic examinations.

Purpose of the Study:

To review diseases associated with CNV secondary to uveitis.
To highlight novel treatment modalities and therapeutic strategies for CNV.

Main Methods:

Diagnostic imaging techniques including fluorescein angiography (FA), indocyanine green angiography (ICGA), and optical coherence tomography (OCT) are crucial for characterizing CNV.
Identifying underlying infectious causes is important for targeted therapy.
Management of noninfectious uveitis involves controlling inflammation with systemic corticosteroids and immunosuppressants, even in subclinical cases.

Main Results:

Accurate diagnosis of CNV requires thorough examination and advanced imaging.
Treatment strategies focus on addressing the underlying cause (infection or inflammation).
Intravitreal anti-Vascular Endothelial Growth Factor (VEGF) agents are recommended for refractory cases.

Conclusions:

CNV secondary to uveitis results in significant visual impairment.
ICGA is essential for assessing choroidal status.
Current evidence is limited to case reports and small series, necessitating further clinical trials to establish treatment guidelines.