Related Experiment Video
Updated: Jun 13, 2026
04:12
Modeling Posthemorrhagic Hydrocephalus of Prematurity in Rats
Published on: March 28, 2025
[Multiple splenic abscesses associated with normotensive hydrocephaly]
M Antonescu1, C Matei, I Matei
1Clinica Chirurgie II, Spitalul Clinic Judeţean de Urgenţă, Sibiu, Romania. marius_antonescu10@yahoo.co.nz
Chirurgia (Bucharest, Romania : 1990)
|April 22, 2010
Summary
This study reports a rare case of multiple splenic abscesses in an elderly patient with normotensive hydrocephaly. A combined surgical team successfully treated the patient with a one-stage ventriculo-cardiac shunting and splenectomy procedure.
Area of Science:
- Medicine
- Surgery
- Neurosurgery
Background:
- Splenic abscesses are uncommon but serious infections.
- Normotensive hydrocephaly can present with varied neurological symptoms.
- Combined surgical approaches are complex and require multidisciplinary teams.
Observation:
- An elderly patient presented with an unusual co-occurrence of multiple splenic abscesses and normotensive hydrocephaly.
- The condition necessitated a complex, simultaneous surgical intervention.
Findings:
- A successful one-stage surgical procedure involving ventriculo-cardiac shunting and splenectomy was performed.
- The patient experienced a favorable outcome following the combined surgical approach.
Implications:
- This case highlights the possibility of managing multiple splenic abscesses and adult hydrocephaly concurrently.
- It underscores the efficacy of a multidisciplinary surgical team in treating complex, co-existing conditions.
- This report may inform future treatment strategies for similar rare presentations.
Related Concept Videos
01:26Brain Abscess l: Introduction
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
01:14Increased Intracranial Pressure l: Introduction
Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
01:22Cerebral Edema ll: Pathophysiology
Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...
01:22Portal Hypertension
Portal hypertension is an increase in blood pressure within the portal venous system. Normally, this pressure is less than 5 mmHg. It is considered clinically significant when it rises above 10 mmHg. At this threshold, complications from altered blood flow and venous congestion emerge.EtiologyPortal hypertension arises from conditions that impede blood flow through the liver. The most common cause is cirrhosis, in which chronic liver injury leads to fibrotic scarring. This fibrosis narrows or...
01:17Hemorrhagic Stroke l: Introduction
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
01:29Hepatic Encephalopathy
DefinitionHepatic encephalopathy is a reversible neurologic syndrome that results from advanced liver dysfunction or portosystemic shunting. It leads to disturbances in cognition, behavior, and motor function due to the brain’s exposure to gut-derived toxins that the liver fails to detoxify.EtiologyThis condition develops either in the setting of acute fulminant hepatitis or progressively during chronic liver disease, such as cirrhosis and portal hypertension. Portosystemic shunting—including...