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In vivo cleaved CDCP1 promotes early tumor dissemination via complexing with activated β1 integrin and induction of FAK/PI3K/Akt motility signaling.

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Blocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells.

Oncogene·2011

Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP). The role of the cytoplasmic tail Cys(574), the active site Glu(240), and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in breast carcinoma cells.

The Journal of biological chemistry·2001

Growth factor-induced angiogenesis in vivo requires specific cleavage of fibrillar type I collagen.

Blood·2001

The isolation, characterization, and molecular cloning of a 75-kDa gelatinase B-like enzyme, a member of the matrix metalloproteinase (MMP) family. An avian enzyme that is MMP-9-like in its cell expression pattern but diverges from mammalian gelatinase B in sequence and biochemical properties.

The Journal of biological chemistry·2000

Two-to-one randomization is associated with increased control-arm patient withdrawal.

Journal of the National Cancer Institute·2026

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Journal of the National Cancer Institute·2026

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Journal of the National Cancer Institute·2026

Effectiveness of an exercise intervention on cognition in breast cancer survivors: a randomized controlled trial.

Journal of the National Cancer Institute·2026

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Journal of the National Cancer Institute·2026

Early palliative care for African American and rural-dwelling advanced cancer family caregivers: long-term outcomes.

Journal of the National Cancer Institute·2026

Macrophage Trogocytosis of Tumor Cells Drives the Immunosuppression of Tumor Microenvironment.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Cardiac intimal sarcoma presenting with pseudo-pulmonary embolism: surgical debulking, RVOT reconstruction and pulmonary valve replacement.

Multimedia manual of cardiothoracic surgery : MMCTS·2026

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Frontiers in immunology·2026

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Journal of clinical laboratory analysis·2026

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The Limulus Blood Cell Secretes α2-Macroglobulin When Activated.

In vivo cleaved CDCP1 promotes early tumor dissemination via complexing with activated β1 integrin and induction of FAK/PI3K/Akt motility signaling.

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Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP). The role of the cytoplasmic tail Cys(574), the active site Glu(240), and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in breast carcinoma cells.

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