Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hypopituitarism.

R D Blondell1

  • 1University of Louisville School of Medicine, Kentucky.

American Family Physician
|June 1, 1991
PubMed
Summary
This summary is machine-generated.

Hypopituitarism, or underactive pituitary gland, disrupts hormone regulation. Causes range from tumors to trauma, requiring lifelong hormone replacement and disease management.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Can recovering alcoholics help hospitalized patients with alcohol problems?

The Journal of family practice·2001
Same author

Disorders of puberty.

American family physician·1999
Same author

Which medical school applicants will become generalists or rural-based physicians?

The Journal of the Kentucky Medical Association·1998
Same author

The practicality of using the SMAST and AUDIT to screen for alcoholism among adolescents in an urban private family practice.

The Journal of the Kentucky Medical Association·1997
Same author

Alcoholism. Taking a preventive, public health approach.

Postgraduate medicine·1996
Same author

Abdominal pain. What happens in primary care?

Archives of family medicine·1996
Same journal

For Post-stent Patients With Atherosclerotic Coronary Vascular Disease Who Are Taking an Anticoagulant, Adding Aspirin Worsens Outcomes.

American family physician·2026
Same journal

Nausea and Vomiting During Pregnancy.

American family physician·2026
Same journal

Metabolic Dysfunction-Associated Steatotic Liver Disease: Diagnosis and Management.

American family physician·2026
Same journal

Aerobic Exercise Is the Better Exercise Modality for Knee Osteoarthritis.

American family physician·2026
Same journal

Overscreening Leads to Overdiagnosis of MASLD.

American family physician·2026
Same journal

Type 2 Diabetes: Outpatient Insulin Management.

American family physician·2026
See all related articles

Area of Science:

  • Endocrinology
  • Neuroendocrinology

Background:

  • The pituitary gland is central to the endocrine system, controlling hormone release via feedback loops with the hypothalamus and target glands.
  • Pituitary function is essential for regulating thyroid, adrenal, gonadal axes, and metabolic homeostasis.

Observation:

  • Hypopituitarism arises from diverse causes like cancer, ischemia, infection, developmental issues, and trauma, affecting either the pituitary (primary) or hypothalamus (secondary).
  • Clinical manifestations vary based on the lesion's location and extent, potentially causing hypothyroidism, adrenal insufficiency, diabetes insipidus, hypoglycemia, sexual dysfunction, and growth retardation.

Findings:

  • Diagnosis relies on comprehensive clinical history, physical examination, endocrine function tests, and pituitary/sella turcica imaging.
  • Identifying the specific cause is crucial for appropriate management.

Related Experiment Videos

Implications:

  • Treatment typically involves lifelong hormone replacement therapy and addressing the underlying etiology through medical or surgical interventions.
  • Effective management of hypopituitarism is vital for restoring endocrine balance and improving patient quality of life.