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Updated: Jun 13, 2026

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions
Published on: July 22, 2013
Carbon nanotube transistor controlled by a biological ion pump gate
Shih-Chieh J Huang1, Alexander B Artyukhin, Nipun Misra
1Molecular Biophysics and Functional Nanostructures Group, Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, CA, USA.
Abstract:
We report a hybrid bionanoelectronic transistor that has a local ATP-powered protein gate. ATP-dependent activity of a membrane ion pump, Na(+)/K(+)-ATPase, embedded in a lipid membrane covering the carbon nanotube, modulates the transistor output current by up to 40%. The ion pump gates the device by shifting the pH of the water layer between the lipid bilayer and nanotube surface. This transistor is a versatile bionanoelectronic platform that can incorporate other membrane proteins.
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