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Method to Visualize and Analyze Membrane Interacting Proteins by Transmission Electron Microscopy
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Membrane protein clusters at nanoscale resolution: more than pretty pictures

Thorsten Lang1, Silvio O Rizzoli

  • 1LIMES-Institute, Laboratory of Membrane Biochemistry, University of Bonn, Bonn.

Physiology (Bethesda, Md.)
|May 1, 2010
PubMed

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Mechanisms of Membrane Domain Formation00:59

Mechanisms of Membrane Domain Formation

Different physical properties of lipids and proteins allow them to localize and form distinct islands or domains in the membrane. Some membrane domains are formed due to protein-protein interactions, whereas others are formed due to the presence of specific lipids such as sphingolipids and sterols—for example, large proteins, such as bacteriorhodopsin, aggregate and create distinct domains.
Another mechanism for membrane domain formation involves membrane proteins interacting with cytoskeletal...