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A case of acute q Fever with severe acute cholestatic hepatitis
Hyun Cheul Choi1, Sang Hyub Lee, Junghee Kim
1Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Abstract:
Minimal hepatic dysfunction can be common in acute Q fever, but severe acute cholestatic hepatitis is rarely reported. We report on a 55-year-old male with acute Q fever and severe acute cholestatic hepatitis. He complained of fever, jaundice, ascites, and restlessness on admission. A liver biopsy revealed the presence of compact fibrin-ring granulomas. Serologic titers for C. burnetii IgM and IgG were 2048:1 and 1024:1, respectively. C. burnetii DNA was detected by a nested polymerase chain reaction on the liver tissue.
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