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Updated: Jun 13, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Conjunctival plasmacytoma.

Jasmine W Yumori¹, Pauline Ilsen, David C Bright

¹West Los Angeles Veterans Affairs Health Center, Los Angeles, California, USA. jyumori@westernu.edu

Optometry (St. Louis, Mo.)

|May 4, 2010

Summary

This summary is machine-generated.

This case report details a rare conjunctival plasmacytoma in a 33-year-old man. Early diagnosis via biopsy and appropriate treatment are crucial for managing this plasma cell tumor.

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Area of Science:

Ophthalmology
Oncology
Pathology

Background:

Plasmacytomas are plasma cell neoplasms that can be primary or secondary, with secondary tumors often linked to multiple myeloma.
Extramedullary plasmacytomas, tumors arising outside the bone marrow, are uncommon.
Conjunctival involvement by plasmacytoma is exceptionally rare.

Observation:

A 33-year-old male presented with bilateral eye redness, predominantly in the right eye.
A vascularized lesion was identified on the conjunctiva of the right eye.
The lesion was biopsied for histopathological examination.

Findings:

The excisional biopsy confirmed the diagnosis of conjunctival plasmacytoma.
Histopathologic examination is the gold standard for definitive diagnosis.
This case highlights a rare presentation of a plasma cell tumor.

Implications:

Conjunctival plasmacytomas, though rare, warrant clinical awareness due to potential association with multiple myeloma.
Treatment options include local excision, external beam radiation, or radiotherapy post-excision.
Long-term systemic follow-up is essential to rule out underlying multiple myeloma or recurrence.