Related Experiment Video
Updated: May 2, 2026
07:44
In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
3.0K
Optical coherence tomography findings in ocular argyrosis.
Ophthalmic Surgery, Lasers & Imaging Retina
|February 20, 2014
Summary
Colloidal silver ingestion can cause ocular argyrosis, a unique geographic maculopathy. This condition presents with slate gray skin, drusenoid deposits, and severe choroidal thinning.
Area of Science:
- Ophthalmology
- Toxicology
Background:
- Colloidal silver supplements are widely available.
- Systemic absorption of silver can lead to tissue deposition.
Observation:
- A 68-year-old man with a history of daily colloidal silver ingestion presented with slate gray skin discoloration.
- Ophthalmic examination revealed bilateral perimacular drusenoid deposits and marked choroidal thinning.
Findings:
- Optical coherence tomography (OCT) showed drusenoid deposits anterior to the inner segment ellipsoid band.
- Fluorescein angiography demonstrated a "silent choroid" pattern.
- Elevated serum silver levels confirmed systemic silver accumulation.
Implications:
- This case highlights ocular argyrosis as a potential consequence of chronic colloidal silver use.
- The findings suggest a link between systemic silver deposition and specific maculopathy patterns.
- Further research is needed to understand the long-term ocular effects of silver exposure.
More Related Videos
Related Concept Videos
01:25Glaucoma: Overview
1.7K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.7K
01:27Open Angle Glaucoma: Treatment
1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K