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Focal Laser Photocoagulation for Large, Persistent Retinal Pigment Epithelial Detachment: A Case Series
Jun Young Ha1, Jae Eun Kang1, Yun Sik Yang1,2
1Department of Ophthalmology, Wonkwang University Hospital, Wonkwang University College of Medicine, Iksan.
Background And Objective:
This study aimed to describe outcomes of focal laser photocoagulation for large, persistent pigment epithelial detachment (PED).
Patients And Methods:
Ten eyes underwent focal 577-nm yellow laser photocoagulation at the peripheral PED margin and were reviewed for 6 months, longer when available.
Results:
Eight eyes achieved complete PED regression within 6 months: four predominantly serous, two mixed serous-fibrovascular with inactive type 1 choroidal neovascularization (CNV), and two with polypoidal choroidal vasculopathy. In mixed and polypoidal lesions, regression predominantly involved the serous component. The mean time to regression was 2.5 months, and best-corrected visual acuity improved from 0.41 to 0.25 logMAR. Two eyes with active type 1 CNV showed incomplete responses. Seven eyes maintained regression over a mean 49.9-month follow-up. No laser-related complications occurred.
Conclusion:
Focal laser photocoagulation was associated with regression of large, persistent PEDs, with responses influenced by lesion composition and neovascular activity. These preliminary findings require confirmation in larger controlled studies.