Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clearance Models: Compartment Models01:25

Clearance Models: Compartment Models

Clearance measures drug elimination from the central compartment, including plasma and highly perfused organs like kidneys and liver. Its calculation varies depending on pharmacokinetic models and administration routes. The one-compartment model, for instance, portrays the pharmacokinetics of polar drugs such as aminoglycoside antibiotics administered intravenously and readily excreted in urine. In this case, clearance is influenced by the terminal rate constant (λz) and the total volume of...
Compartment Models: Two-Compartment Model01:20

Compartment Models: Two-Compartment Model

The two-compartment model divides the body into central and peripheral compartments to account for varying blood perfusion rates among organs and tissues, affecting drug distribution. The central compartment includes blood and highly perfused tissues with rapid drug distribution, while the peripheral compartment contains tissues with slower drug distribution. After a single IV bolus dose, the drug concentration is high in plasma and low in tissues. The drug distribution between compartments...
Data Reporting and Recording01:24

Data Reporting and Recording

Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
Clearance Models: Noncompartmental Models01:17

Clearance Models: Noncompartmental Models

Clearance is a pharmacokinetic parameter traditionally defined by compartment models, signifying the rate at which a drug is expelled from the body. However, a noncompartmental model offers an alternative method for assessing clearance, primarily employing empirical data obtained after administering a single drug dose.
The noncompartmental approach capitalizes on extensive sampling data, correlating the volume of distribution to systemic exposure and the administered dosage. This method enables...
Compartment Models: Single-Compartment Model01:14

Compartment Models: Single-Compartment Model

The single-compartment model serves as a simplified representation of the human body. This model assumes that the body functions as a single, well-mixed open compartment. When a drug is administered intravenously, it enters the body and quickly distributes uniformly. The drug then undergoes biotransformation and elimination, ultimately leaving the body. The volume of this compartment is referred to as the apparent volume of distribution into which the drug can uniformly distribute. In this...
Data Collection II01:29

Data Collection II

The nursing history captures and records the patient's health status, so that a care plan evolves to meet the patient's individual needs. The nursing health history is a part of the initial assessment. A comprehensive history covers all health dimensions and plays a significant role in the assessment process. A comprehensive history includes the patient's biographical information, reasons for seeking health care, expectations, present and past health history, medications, and family,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A sequential model of two-choice intensity identification.

Frontiers in cognition·2026
Same author

What is prepared in temporal preparation? A review and a historical appreciation.

Frontiers in psychology·2026
Same author

[Doping in recreational sports].

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·2026
Same author

Ten years Diffusion Model for Conflict (DMC) tasks: Theoretical foundations, applications, practical recommendations, and open challenges.

Psychonomic bulletin & review·2026
Same author

The time-intensity uncertainty principle in vision.

Attention, perception & psychophysics·2026
Same author

Internal reference updating in visual duration discrimination: A search for boundary conditions : Internal reference updating.

Attention, perception & psychophysics·2026
Same journal

Low prevalence targets are primarily missed due to mind wandering.

Attention, perception & psychophysics·2026
Same journal

An introduction to the special issue celebrating Mary A. Peterson.

Attention, perception & psychophysics·2026
Same journal

Properties of the threshold stimulus exposure duration (TSED) measure of visual search efficiency.

Attention, perception & psychophysics·2026
Same journal

Auditory selective attention in depth: Investigating directional dependency across front, lateral, and rear spaces.

Attention, perception & psychophysics·2026
Same journal

Dissociations between stereoacuity and visual acuity with binocular night vision goggles.

Attention, perception & psychophysics·2026
Same journal

Reward-based prioritization and perceptual feature effects on attentional flexibility in working memory.

Attention, perception & psychophysics·2026
See all related articles

Related Experiment Video

Updated: Jun 13, 2026

Revised and Neuroimaging-Compatible Versions of the Dual Task Screen
07:52

Revised and Neuroimaging-Compatible Versions of the Dual Task Screen

Published on: October 5, 2020

DLs in reminder and 2AFC tasks: data and models.

Rolf Ulrich1

  • 1Abteilung für Allgemeine und Biologische Psychologie, Psychologisches Institut, Universität Tübingen, Tübingen, Germany. ulrich@uni-tuebingen.de

Attention, Perception & Psychophysics
|May 4, 2010
PubMed
Summary
This summary is machine-generated.

The two-alternative forced choice (2AFC) task yields larger difference limen (DL) estimates than the reminder task. This study clarifies issues overlooked in prior reanalyses, advancing accurate discrimination performance assessment in 2AFC tasks.

Related Experiment Videos

Last Updated: Jun 13, 2026

Revised and Neuroimaging-Compatible Versions of the Dual Task Screen
07:52

Revised and Neuroimaging-Compatible Versions of the Dual Task Screen

Published on: October 5, 2020

Area of Science:

  • Psychology
  • Psychophysics

Background:

  • The difference limen (DL) is a key measure in sensory discrimination.
  • Debate exists regarding whether the two-alternative forced choice (2AFC) task or the reminder task yields larger DL estimates.

Purpose of the Study:

  • To dispute the reanalysis by García-Pérez and Alcalá-Quintana (2010) concerning 2AFC vs. reminder task DLs.
  • To clarify fundamental properties of 2AFC psychometric functions and Type B order errors.
  • To provide a plausible account for the larger DLs observed in 2AFC tasks.

Main Methods:

  • Reanalysis of psychophysical data.
  • Examination of psychometric function properties.
  • Consideration of Type B order errors.

Main Results:

  • García-Pérez and Alcalá-Quintana's reanalysis overlooked critical aspects of 2AFC tasks.
  • The difference model with guessing does not adequately explain the observed DL differences.
  • 2AFC tasks tend to yield approximately 50% larger DLs than reminder tasks.

Conclusions:

  • The 2AFC task's larger DL estimates are a fundamental property, not an artifact.
  • Proper assessment of discrimination performance requires accounting for 2AFC task characteristics.
  • Further research should consider these factors for accurate psychophysical measurements.