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Related Concept Videos

Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
Autoimmune Disorders01:29

Autoimmune Disorders

Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune system...
Bone Remodeling and Repair01:31

Bone Remodeling and Repair

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...

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Reconstruction of Electric Discharge Patterns and Electrogenesis Mechanism in African Sharptooth Catfish Clarias gariepinus (Clariidae, Siluriformes).

Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections·2021
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Electrogenesis in Two African Upside-Down Catfishes, Synodontis sorex and S. batensoda (Mochokidae, Siluriformes).

Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections·2019
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[Cytomorphometric study on the effect of smoking on tissues adjacent to dental implants].

Stomatologiia·2019
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Rearrangement of the Prefrontal Cortex Neural Activity in Both Hemispheres during Learning.

Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections·2018
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[RATIO OF PREFRONTAL CORTEX NEURAL ACTIVITY BOTH HEMISPHERES DURING TASK OF CHOICE IN THE TWO-RING MAZE].

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Related Experiment Video

Updated: Jun 13, 2026

Using Inducible Osteoblastic Lineage-Specific Stat3 Knockout Mice to Study Alveolar Bone Remodeling During Orthodontic Tooth Movement
05:25

Using Inducible Osteoblastic Lineage-Specific Stat3 Knockout Mice to Study Alveolar Bone Remodeling During Orthodontic Tooth Movement

Published on: July 21, 2023

[Autoimmune states correction for pathologic component (link) elimination that hinder physiologic osteogenesis].

M K Bolotanova, A A Orlov, A V Potemkin

    Stomatologiia
    |May 4, 2010
    PubMed
    Summary

    Gravitational blood surgery stabilizes autoimmune diseases, enabling complex reconstructive operations in the maxillofacial region. This technique improves healing of post-operative wounds in patients with compromised immune systems.

    Related Experiment Videos

    Last Updated: Jun 13, 2026

    Using Inducible Osteoblastic Lineage-Specific Stat3 Knockout Mice to Study Alveolar Bone Remodeling During Orthodontic Tooth Movement
    05:25

    Using Inducible Osteoblastic Lineage-Specific Stat3 Knockout Mice to Study Alveolar Bone Remodeling During Orthodontic Tooth Movement

    Published on: July 21, 2023

    Area of Science:

    • Regenerative Medicine
    • Immunology
    • Oral and Maxillofacial Surgery

    Background:

    • Technological advancements offer new therapeutic options for serious diseases affecting tissue repair.
    • Stomatologists frequently encounter challenges with healing in post-operative bone and soft tissue wounds.
    • A significant patient cohort presents with co-existing autoimmune diseases, complicating wound healing.

    Observation:

    • Patients with autoimmune diseases pose unique challenges for reconstructive surgery due to impaired healing.
    • Individually tailored gravitational blood surgery methods were employed.
    • These methods aimed to stabilize autoimmune conditions and modulate immune status.

    Findings:

    • Successful stabilization of autoimmune diseases was achieved through gravitational blood surgery.
    • Immune system status was effectively corrected in the treated patient group.
    • This correction facilitated uncomplicated reconstructive operations in the maxillofacial region.

    Implications:

    • Gravitational blood surgery presents a viable strategy for managing complex cases in oral and maxillofacial surgery.
    • The technique shows promise for improving outcomes in patients with autoimmune disorders requiring reconstructive procedures.
    • This approach may broaden the scope of surgical interventions for patients with compromised healing capacities.