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A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

Spontaneous renal artery dissection.

Santhosh G John¹, Unnikrishnan Pillai, Philip B Vaidyan

¹Department of Internal Medicine, Saint Mary's Health Center in St. Louis, USA. santhoshgj2000@gmail.com

Missouri Medicine

|May 8, 2010

Summary

This summary is machine-generated.

Spontaneous renal artery dissection (SRAD) is rare, often linked to other conditions. This case highlights a spontaneous left renal artery dissection and kidney infarction in a patient with positive antiphospholipid antibodies.

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Area of Science:

Nephrology
Vascular Surgery
Rheumatology

Background:

Spontaneous renal artery dissection (SRAD) is an uncommon condition, frequently associated with pre-existing renal artery pathologies.
While rare, isolated spontaneous dissections necessitate thorough investigation into potential underlying causes.

Observation:

A case of spontaneous dissection of the left main renal artery was identified.
The patient presented with infarction of the left kidney and tested positive for antiphospholipid antibodies.

Findings:

Diagnostic imaging confirmed the diagnosis of spontaneous renal artery dissection (SRAD).
The presence of antiphospholipid antibodies was noted in conjunction with the arterial dissection.

Implications:

Antiphospholipid antibodies may contribute to arterial dissection pathogenesis through endothelial dysfunction.
This case represents a novel association and the first literature report linking antiphospholipid antibodies to spontaneous renal artery dissection.