Related Experiment Video
Updated: Jun 13, 2026

Immunoglobulin G N-Glycan Analysis by Ultra-Performance Liquid Chromatography
Published on: January 18, 2020
Physico-chemical and biological properties of solvent/detergent treated immunoglobuin G preparations
N V Nesterova1, O V Kurkina, V A Samoilenko
1Zabolotny Institute of Microbiology and Virology National Academy of Sciences, 154 Zabolotny St., Kyiv, MSP, DO3680, Ukraine
Abstract:
Protein composition homogeneity, fraction composition, molecular weight composition, anticomplementary activity, anti-A and anti-B haemagglutinins, specific activity, and pyrogens were studied in intramuscular and intravenous immunoglobulin G preparations, treated and non-treated with solvent/detergent mixture for virus inactivation. Physico-chemical and biological properties retention is shown. Quality of immunoglobulin preparations was improved due to purification by the methods of anion- and cation- exchange preparative low pressure liquid chromatography.
Related Concept Videos
Detergent Purification of Membrane Proteins
Solubility
A solution is a homogeneous mixture composed of a solvent, the major component, and a solute, the minor component. The physical state of a solution—solid, liquid, or gas—is typically the same as that of the solvent. Solute concentrations are often described with qualitative terms such as dilute (of relatively low concentration) and concentrated (of relatively high concentration).
In a solution, the solute particles (molecules, atoms, and/or ions)...
Chemical and Solubility Equilibria
Immunoprecipitation
Chromatin Immunoprecipitation
Chromatin immunoprecipitation, also known as ChIP, is used to study protein-DNA or...
The Colloidal State
Colloids

