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Schizotypy and altered digit ratios: a second look.
Diane Carol Gooding1, Madeline Johnson, Joel Stephen Peterman
1University of Wisconsin-Madison, Department of Psychology, Madison, WI 53706, USA. dgooding@wisc.edu
Psychiatry Research
|May 18, 2010
Summary
Digit ratio differences are not linked to positive or negative schizotypy. This study questions the use of digit ratios as a reliable indicator for schizophrenia-spectrum disorders.
Area of Science:
- Neuroscience
- Psychiatry
- Developmental Psychology
Background:
- The 2D:4D digit ratio has been proposed as a biomarker for neurodevelopmental disorders.
- Schizotypy, characterized by positive and negative symptoms, shares some features with schizophrenia spectrum disorders.
Purpose of the Study:
- To investigate the association between digit ratios and schizotypy.
- To examine the relationship between schizotypy, Theory of Mind, and affect.
Main Methods:
- Compared digit ratios in individuals with positive schizotypy, negative schizotypy, and controls.
- Assessed Theory of Mind using the Reading the Mind in the Eyes Test (RMET).
- Measured trait affect using the Positive and Negative Affect Schedule (PANAS).
Main Results:
- No significant differences in digit ratios were found between schizotypy groups and controls.
- No significant differences in Theory of Mind performance were observed across the groups.
- A significant inverse association was found between Theory of Mind and negative affect.
Conclusions:
- Digit ratios do not appear to be a reliable indicator for schizophrenia-spectrum disorders.
- Findings challenge the utility of digit ratios in predicting neurodevelopmental risks.
- Theory of Mind performance is inversely related to negative affect in schizotypy.
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