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[T-lymphocyte subpopulations in chronic active hepatitis]
T Fucíková1, M Brodanová, J Bartůnková
1Oddĕleni klinické imunologie 1. lékarské fakulty Univerzity Karlovy, Praha.
Abstract:
In 33 patients with chronic active hepatitis quantitative changes were found in the ratio of different sub-populations of T lymphocytes in the peripheral blood stream which were either associated with treatment or with the presence of HbsAg in serum. A reduction of CD 3 positive lymphocytes was found in patients not treated by immunosuppression. In HbsAg positive patients an increase of CD 4 positive lymphocytes was found, as compared with HBsAg negative patients. Signs of activity of the hepatic process correlated with the presence of sign CD 8.