Related Experiment Video
Updated: Jun 12, 2026

Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis
Published on: October 17, 2016
Vulvar melanocytic nevi: a dermoscopic investigation
Annarosa Virgili1, Maria Rosaria Zampino, Andrea Marzola
1Department of Clinical and Experimental Medicine, University of Ferrara, Ferrara, Italy. vri@unife.it
Background:
Very few dermoscopic investigations into pigmented genital lesions have been performed to date. To the best of our knowledge, no dermoscopical description of vulvar melanocytic nevi (MN) has yet been proposed.
Objective:
Our aims were to analyze the dermoscopic features of vulvar MN and to review the literature of dermoscopy of the vulvar area.
Methods:
Among 74 women presenting 84 vulvar pigmented lesions, 10 who received a visual diagnosis of MN were submitted to dermoscopic and histopathological analysis.
Results:
Histology confirmed the clinical diagnosis of MN in 8 out of 10 cases, while the remaining 2 pigmented lesions were diagnosed as seborrheic keratosis. Vulvar MN were generally found to share similar dermoscopic patterns with their cutaneous equivalent.
Conclusions:
Although further observation will be necessary to provide additional data and establish key morphological criteria and/or algorithms useful for differentiating between melanocytic and nonmelanocytic vulvar lesions, dermoscopy should be considered an investigative tool, as clinical observation alone may not be sufficient for accurate diagnosis.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Papillary Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...

