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Updated: Jun 12, 2026

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
Published on: October 10, 2025
[Sudden growth of previously indolent scalp nodule]
R Schmaltz1, C S L Müller, T Vogt
1Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum des Saarlandes, 66421, Homburg, Germany. rebecca.schmaltz@uniklinikum-saarland.de
Abstract:
Cylindromas are benign adnexal tumors with eccrine and apocrine differentiation. They may appear in combination with spiradenomas and trichoepitheliomas in patients with the Brooke-Spiegler syndrome. Malignant changes are rare; possible clues are ulceration, bleeding or sudden growth of the lesions. Cylindromas are often removed for cosmetic reasons. We present a case of scalp cylindromatosis in which a primary cutaneous adenoid-cystic carcinoma developed. The patient was treated with local surgical excision. As our case shows, histological evaluation is mandatory, even when the clinical diagnosis seems obvious.
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