Related Experiment Video
Updated: Jun 12, 2026

Catalytic Reactions at Amine-Stabilized and Ligand-Free Platinum Nanoparticles Supported on Titania During Hydrogenation of Alkenes and Aldehydes
Published on: June 24, 2022
Recent developments on chiral P,S-type ligands and their applications in asymmetric catalysis
Fuk Loi Lam1, Fuk Yee Kwong, Albert S C Chan
1Open Laboratory of Chirotechnology of the Institute of Molecular Technology for Drug Discovery and Synthesis and Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong.
Abstract:
This feature article illustrates new concepts and approaches for designing new P,S-mixed donor chelating ligands based on three major types of chiral skeleton, the central, axial and planar chirality. The versatility in structural modification is highlighted. It offers an effective pathway to access scientifically useful chiral ligands of diverse electronic and steric properties for optimization in various catalytic enantioselective transformations. In this article, the applications of these optically active ligands in a variety of asymmetric catalytic reactions will be discussed with reference to updated literature findings as well as the author's original research.
More Related Videos
08:25Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks (MOFs)
Published on: January 17, 2020
19:58Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
Published on: July 30, 2017
Related Concept Videos
Reduction of Alkenes: Asymmetric Catalytic Hydrogenation
The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...
Chirality at Nitrogen, Phosphorus, and Sulfur
A consequence of chirality is the need for enantiomeric resolution. While this is theoretically possible for all...
Prochirality
Chirality in Nature
Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration
SN2 Reaction: Stereochemistry
If the substrate is an achiral molecule at the α-carbon, the inversion of configuration is not observed.