Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 12, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
12:21

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

The "Task B problem" and other considerations in developmental functional neuroimaging.

Jessica A Church1, Steven E Petersen, Bradley L Schlaggar

  • 1Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

Human Brain Mapping
|May 25, 2010
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Functional brain organization is stable within individuals across years.

bioRxiv : the preprint server for biology·2026
Same author

Patterns of brain-wide associations reflect socioeconomics.

Science (New York, N.Y.)·2026
Same author

Altered neurodevelopmental trajectories of brain structure in Tourette syndrome and Chronic Tic Disorders.

medRxiv : the preprint server for health sciences·2026
Same author

Precision fMRI reveals densely interdigitated network patches with conserved motifs in the lateral prefrontal cortex.

Neuron·2026
Same author

Parallel processing chains span cytoarchitectures to organize association cortex.

bioRxiv : the preprint server for biology·2026
Same author

The interplay between executive function and learning disabilities: Developmental cognitive neuroscience perspectives on reading, math, and ADHD.

Developmental cognitive neuroscience·2026
Same journal

Diurnal Variations and Test-Retest Reliability of Resting-State Functional MRI Metrics.

Human brain mapping·2026
Same journal

Brain Aging in Specific Phobia: An ENIGMA-Anxiety Mega-Analysis.

Human brain mapping·2026
Same journal

Talking to the Brain: Using Large Language Models as Proxies to Model Brain Semantic Features.

Human brain mapping·2026
Same journal

Emotional Context Modulates the Response to Somatosensory Stimuli Within 20 milliseconds.

Human brain mapping·2026
Same journal

GABAergic Modulation of Brain Function During Prosaccade and Antisaccade Eye Movements: Evidence From Ultra-High-Field fMRI.

Human brain mapping·2026
Same journal

Injury Severity Influences Long-Term Cognitive Control in Pediatric "Mild" Traumatic Brain Injury.

Human brain mapping·2026
See all related articles

Functional neuroimaging, especially fMRI, offers safe cognitive study across lifespans. This article addresses key methodological challenges for imaging children, including performance, movement, and data analysis for reliable results.

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Medical Imaging

Background:

  • Functional neuroimaging techniques like fMRI are valuable for studying cognition throughout life and in specific groups.
  • Methodological challenges exist in functional neuroimaging, particularly when studying pediatric populations.
  • Understanding these challenges is crucial for accurate interpretation of neuroimaging data.

Purpose of the Study:

  • To discuss critical methodological issues pertinent to functional neuroimaging in children.
  • To provide strategies for addressing common challenges in pediatric neuroimaging research.
  • To explore implications for interpreting functional neuroanatomical differences and BOLD signal changes.

Main Methods:

  • Review of methodological considerations in functional neuroimaging.

More Related Videos

Transferring Cognitive Tasks Between Brain Imaging Modalities: Implications for Task Design and Results Interpretation in fMRI Studies
10:09

Transferring Cognitive Tasks Between Brain Imaging Modalities: Implications for Task Design and Results Interpretation in fMRI Studies

Published on: September 22, 2014

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis
10:33

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis

Published on: June 20, 2012

Related Experiment Videos

Last Updated: Jun 12, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
12:21

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

Transferring Cognitive Tasks Between Brain Imaging Modalities: Implications for Task Design and Results Interpretation in fMRI Studies
10:09

Transferring Cognitive Tasks Between Brain Imaging Modalities: Implications for Task Design and Results Interpretation in fMRI Studies

Published on: September 22, 2014

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis
10:33

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis

Published on: June 20, 2012

  • Discussion of task performance assessment and group differences.
  • Examination of movement control, statistical power, atlas registration, and data analysis strategies.
  • Exploration of developmental neurovascular differences and interpretation of negative BOLD signals.

    • Main Results:

    • Identified key methodological issues in pediatric functional neuroimaging.
    • Proposed strategies for enhancing data quality and interpretation in child studies.
    • Highlighted the importance of considering developmental factors and signal interpretation nuances.

    Conclusions:

    • Addressing methodological challenges is essential for robust pediatric neuroimaging research.
    • Careful consideration of performance, movement, statistical power, and registration improves data reliability.
    • Understanding developmental neurovascular differences and BOLD signal interpretation is critical for accurate conclusions.